Recombination at Long Mutant Telomeres Produces Tiny Single- and Double-Stranded Telomeric Circles
نویسندگان
چکیده
منابع مشابه
Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination
Some human cancers maintain their telomeres using the alternative lengthening of telomeres (ALT) mechanism; a process thought to involve recombination. Different types of recombinational telomere elongation pathways have been identified in yeasts. In senescing yeast telomerase deletion (ter1-Delta) mutants with very short telomeres, it has been hypothesized that copying a tiny telomeric circle ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2005
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.25.11.4406-4412.2005